TIME AND PLACE
The course takes place 4 – 15 November 2024 in the Milan Hašek Auditorium of the Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Vídeňská 1083, Praha 4 Krč (Krč campus of the biological institutes of the Czech Academy of Sciences).
In case of COVID-19 restrictions preventing the course on site, lectures will be streamed via Zoom.
PROGRAM OF THE COURSE
All lectures will be given in English by active scientists.
The course consists of 43 lectures organized into the following thematic blocks:
RNA: organization and regulation of RNA polymerase II transcription, noncanonical RNA caps, transcription and splicing regulation, non-coding RNAs, small RNA pathways.
Proteins: eukaryotic protein synthesis, ribosome structure, structural biology tools, proteomics and proteomes, prions.
Cell biology and signaling: microtubules and signal transduction, microtubules in neuronal development, cytoskeleton and plant organelles, centrosomes and cilia, integrative biology of intermediate microfilaments.
Developmental biology: oocyte-to-zygote transition, planarian regeneration, induced pluripotent stem cells and organoids, zebrafish as a model system in developmental biology, comparative developmental biology of facial shape.
Biomedicine – genomics: rare genetic variants in Mendelian complex diseases, high-throughput sequencing methods, epigenetic disorders and therapy, antiviral prospects of gene editing, base and prime editors.
Biomedicine – cancer biology: germline mutations in cancer, ADP-ribose metabolism and DNA breaks in human disease, fibroblasts in mammary gland development and breast cancer, mitochondria and liver regeneration, ovarian cancer and extracellular vesicles.
Biomedicine – hematology & immunology: regulation of production of immune cells, immune memory, molecular tricks of bacterial pathogens to manipulate the host, central and peripheral immune tolerance, autoimmunity.
ACCOMMODATION AND CATERING
Accommodation for participants from universities outside of Prague needs to be arranged individually in colleges of the Charles University. Course attendees should contact as soon as possible by e-mail the Central reservation office (reservace@kam.cuni.cz) to inquire about available space and mention that they participate in the course.
Catering during the course includes two coffee breaks, one in the morning session and one in the afternoon session. Lunches can be obtained individually in two canteens in the Krč campus during lunch breaks.
TRAVEL DETAILS
Bus line 138 takes you from the Kačerov underground line C station directly to the front gate (“Ústavy Akademie věd” stop) of the campus. Bus line 193 takes you from the Budějovická underground line C station to the stop “Zelené domky” from where you have to walk back for about 200 meters to the front gate of the campus.