TIME AND PLACE
The course takes place 3 – 14 November 2025 in the Milan Hašek Auditorium of the Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Vídeňská 1083, Praha 4 Krč (Krč campus of the biological institutes of the Czech Academy of Sciences).
In case of COVID-19 restrictions preventing the course on site, lectures will be streamed via Zoom.
PROGRAM OF THE COURSE
All lectures will be given in English by active scientists.
The course consists of 43 lectures organized into the following thematic blocks:
RNA: organization and regulation of RNA polymerase II transcription, RNA and innate immunity, non-coding RNAs, RNA & cellular structures.
Proteins: eukaryotic protein synthesis, proteomics and proteomes, structural biology tools, prions, synthetic protein biology.
Cell biology and signaling: integrative biology of intermediate microfilaments, biophysics of ciliary transport, actomyosin in early embryo morphogenesis, interaction between cells and the extracellular matrix, microtubules and signal transduction.
Developmental biology: evo-devo of animal development, early mouse development, zebrafish as a model system in developmental biology, zebrafish as a model system in developmental biology, transposable elements in mammalian development.
Biomedicine – genomics: rare genetic variants in Mendelian complex diseases, sequencing methods, RNA delivery particles, CRISPR and synthetic biology, genetic engineering.
Biomedicine – cancer biology: horizontal mitochondrial transfer in cancer, roles of tumor suppressor p53, metabolic communication in tumors, DNA repair and human pathologies, chromosomal aberrations in cancer cells.
Biomedicine – hematology & immunology: CAR-T biology & therapy, metabolic rewiring in leukemia therapy resistance, tumor immunology and cancer immunotherapy, oxygen transport at the molecular level, non-coding RNAs in leukemias and lymphomas.
ACCOMMODATION AND CATERING
Accommodation for participants from universities outside of Prague needs to be arranged individually in colleges of the Charles University. Course attendees should contact as soon as possible by e-mail the Central reservation office (reservace@kam.cuni.cz) to inquire about available space and mention that they participate in the course.
Catering during the course includes two coffee breaks, one in the morning session and one in the afternoon session. Lunches can be obtained individually in two canteens in the Krč campus during lunch breaks.
TRAVEL DETAILS
Bus line 138 takes you from the Kačerov underground line C station directly to the front gate (“Ústavy Akademie věd” stop) of the campus. Bus line 193 takes you from the Kačerov underground line C station to the stop “Zelené domky” from where you have to walk back for about 200 meters to the front gate of the campus.