TIME AND PLACE
The course takes place 2–13 November 2026 in the Milan Hašek Auditorium of the Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Vídeňská 1083, Praha 4 Krč (Krč campus of the biological institutes of the Czech Academy of Sciences).
PROGRAMME OF THE COURSE
All lectures will be given in English by active scientists.
The course consists of ~ 43 lectures organized into the following thematic blocks:
RNA: transcription and its regulation, non-coding RNAs, RNA caps, transcription and splicing during cell cycle, ribonucleoprotein complexes.
Proteins: eukaryotic protein synthesis, proteomics and proteomes, structural biology tools, CryoEM and CryoET, artificial protein evolution.
Cell biology and signaling: axon navigation via actin oxidation, circadian clock, mechanobiology of development, epithelial homeostasis and cancer, integrative biology of intermediate microfilaments, mitochondrial evolution, cellular logistics, cilia in health and disease.
Developmental biology: oocyte-to-embryo transition, evo-devo of vertebrate evolution, evolution of morphogenesis, zebrafish as a model system in developmental biology, Xenopus as a model for development and regeneration studies.
Biomedicine – genomics: rare genetic variants in Mendelian complex diseases, modeling genetic variants in mouse, nanobodies for therapy, therapeutic vector design and manufacturing, genome editing and beyond.
Biomedicine – cancer biology: cancer predisposition, p53 pathway, DNA strand breaks and human disease, metabolic determinants of metastasis, intestinal tumorigenesis.
Biomedicine – haematology & immunology: haematopoietic stem cells and the immune system formation, immune homeostasis, T-cell biology, haematopoietic disorders.
History of molecular biology in Czechia and at IMG – a minisymposium: history of molecular biology in Czechia, Milan Hašek and his immunogenetics research, Jan Svoboda and his research on retroviruses.
ACCOMMODATION AND CATERING
Accommodation for participants from universities outside of Prague needs to be arranged individually in colleges of the Charles University. Course attendees should contact as soon as possible by e-mail the Central reservation office (reservace@kam.cuni.cz) to inquire about available space and mention that they participate in the course.
Catering during the course includes two coffee breaks, one in the morning session and one in the afternoon session. Lunches can be obtained individually in two canteens in the Krč campus during lunch breaks.
TRAVEL DETAILS
Bus line 138 takes you from the Kačerov underground line C station directly to the front gate (“Ústavy Akademie věd” stop) of the campus.
Bus line 114 takes you from the Kačerov underground line C station to the stop “Zelené domky” from where you have to walk back for about 200 meters to the front gate of the campus.