Programme

50th LECTURE COURSE (2026)

Preliminary programme

MODULE:

DNA/nucleus

Monday 2. 11. 2026
08:40 – 09:00
opening remarks & organizational items, Jiří Jonák / Petr Svoboda
09:00 – 09:50
Compartmentalization of the cell nucleus, lipids and phase separation, Pavel Hozák
09:50 – 10:40
Nuclear lamins and associated proteins: from structure to function in health and disease, Roland Foisner
11:00 – 11:50
Organization of human genome, Jan Pačes
13:00 – 13:50
Spatio-temporal organization of the cell nucleus, Ana Pombo
14:10 – 15:00
Dynamic evolution of telomeres and telomerases, Jiří Fajkus
MODULE:

RNA Biology

Tuesday 3. 11. 2026
09:00 – 09:50
Bacterial RNA polymerase: transcription regulation & stress adaptation, Libor Krásný
09:50 – 10:40
Non-coding RNAs, Jarmila Hnilicová
11:00 – 11:50
Non-canonical RNA caps – from their discovery to their role, Hana Macíčková Cahová
13:00 – 13:50
Cyclin-dependent kinases in transcription and splicing, Dalibor Blažek
14:10 – 15:00
RNA and subcellular architecture – builder and client, Michaela Müller-McNicoll
MODULE:

Proteins

Wednesday 4. 11. 2026
09:00 – 09:50
Translation cycle in bacteria and eukaryotes, Leoš Valášek
09:50 – 10:40
Capabilities and challenges of current proteomics, Jiří Petrák
11:00 – 11:50
Structural biology tools, Václav Veverka
13:00 – 13:50
Deep mutational scanning and deep mutational evolutionary pathway
scanning in protein science and virology, Jiří Zahradník
14:10 – 15:00
Revolution in cryoEM and cryoET, Jiří Nováček
MODULE:

Cell Biology, Cytoskeleton & Co.

Thursday 5. 11. 2026
09:00 – 09:50
Actin oxidation in axon navigation, Daniel Rozbeský
09:50 – 10:40
Circadian clock, Alena Sumová
11:00 – 11:50
Actomyosin-driven early embryo morphogenesis, Teije Corneel Middelkoop
13:00 – 13:50
From cytoskeletal organization to tissue mechanics, Martin Gregor
14:10 – 15:00
Mechanobiology of epithelial homeostasis and cancer, Martijn Gloerich
MODULE:

Cell Biology

Friday 6. 11. 2026
09:00 – 09:50
Mitochondrial evolution: back to basics, Pavel Doležal
09:50 – 10:40
Cellular logistics: membrane trafficking and signaling in health and disease, Marta Miączyńska
11:00 – 11:50
Cilia in health and disease, Martina Huranová
MODULE:

Development

Monday 9. 11. 2026
09:00 – 09:50
Oocyte-to-embryo transition, Helena Fulková
09:50 – 10:40
Evo-Devo, Cristian Miguel Cañestro Garcia
11:00 – 11:50
Patterning during embryonic development, Pavel Tomančák
13:00 – 13:50
Zebrafish as a model system in developmental biology, Peter Fabian
14:10 – 15:00
Xenopus as a model for development and regeneration studies, Radek Šindelka
MODULE:

Biomedicine, Genetics & Genomics

Tuesday 10. 11. 2026
09:00 – 09:50
Rare genetic variants in Mendelian and complex diseases, Stanislav Kmoch
09:50 – 10:40
Modeling genetic variants in mouse – journey from discovery to translation and therapy, Jan Procházka
11:00 – 11:50
Nanobodies for therapy, Jan Konvalinka
13:00 – 13:50
Therapeutic vector design and manufacturing, Varun Tadimarri
14:10 – 15:00
Genome editing and beyond, Michaela Krausová
MODULE:

Biomedicine, Cancer

Wednesday 11. 11. 2026
09:00 – 09:50
DNA strand breaks and human disease, Hana Hanzlíková
09:50 – 10:40
Fueling for a trip: metabolic determinants of metastasis, Mohamed Elgendy
11:00 – 11:50
Intestinal tumorigenesis: from human genetics to experimental mouse models, Lucie Janečková
13:00 – 13:50
Cancer predisposition, Libor Macůrek
14:10 – 15:00
p53 pathway, Zdeněk Andrysík
MODULE:

Biomedicine, Immuno

Thursday 12. 11. 2026
09:00 – 09:50
The architects of immunity: how hematopoietic stem cells build the immune system, Meritxell Alberich Jordà
09:50 – 10:40
Resistance to autoimmunity: the paradox of self-reactive T cells and immune tolerance, Dominik Filipp
11:00 – 11:50
Immune memory saves millions of lives, Ondřej Štěpánek
13:00 – 13:50
Gene-editing strategies for correcting the genetic defects underlying inherited bone marrow failure syndromes, Karolina Škvárová Kramarzová
14:10 – 15:00
Beyond the marrow: biological and clinical insights from extramedullary manifestations of multiple myeloma, David Žihala
MODULE:

50 years minisymposium

Thursday 12. 11. 2026
15:30 – 18:00
Celebrating history of molecular biology in Czechia & research at IMG, Petr Dráber
The emergence and development of molecular genetics, Václav Pačes
Milan Hašek & immunogenetics research, Václav Hořejší
Jan Svoboda & research on retroviruses, Jiří Hejnar
18:00 – 22:00
party & dinner & socializing
MODULE:

Career Development

Friday 13. 11. 2026
09:00 – 10:10
Academic ecosystem, Petr Svoboda
10:40 – 12:00
Scientific misconduct, Petr Svoboda
12:00
Credits