Programme

43rd LECTURE COURSE (2019) – PROGRAMME

The course programme will be published in the coming days.

MODULE:

DNA/nucleus

Monday 4. 11. 2019
08:30 – 09:30
registration, refreshment
09:30 – 09:50
opening remarks, J. Jonák/P. Svoboda
09:50 – 10:40
The nucleus: an old organelle with new structures, P. Hozák
11:00 – 11:50
Human genome structure and evolution, J. Pačes
13:00 – 13:50
Systems biology of regulatory motifs, A. Stark
14:10 – 15:00
Targeted genomic modifications (Mouse genome engineering by CRISPR technology), P. Kašpárek
MODULE:

RNA Biology

Tuesday 5. 11. 2019
09:00 – 09:50
RNA Polymerase: Ready Steady Go!, L. Krásný
09:50 – 10:40
The tale of (more than) two tails: RNA surveillance in eukaryotic cells, S. Vaňáčová
11:00 – 11:50
Regulation of alternative splicing, D. Staněk
13:00 – 13:50
RNA Editing/Modification, M. O’Connell
14:10 – 15:00
Genetic innovation in genome-transposon conflicts, J. Brennecke
MODULE:

Proteins

Wednesday 6. 11. 2019
09:00 – 09:50
Mystery of the Beginning and the End – The Mechanism of Eukaryotic Translation, L. Valášek
09:50 – 10:40
Protein stability, L. Čermák
11:00 – 11:50
Protein structure determination by X-ray crystallography, P. Řezáčová
13:00 – 13:50
Proteins, Proteomes and Proteomics, J. Petrák
14:10 – 15:00
Prions, prion strains and expanding universe of prion diseases, K. Holada
MODULE:

Cell Biology

Thursday 7. 11. 2019
09:00 – 09:50
Cellular iron as a source of oxygen radicals and DNA damage, J. Pláteník
09:50 – 10:40
Biology of eukaryotic flagella and cilia, V. Varga
11:00 – 11:50
Microtubules and signal transduction, Pa. Dráber
13:00 – 13:50
Cellular organelles specific to eukaryotic pathogens, P. Doležal
14:10 – 15:00
DNA repair, H. Hanzlíková
MODULE:

Signaling

Friday 8. 11. 2019
09:00 – 09:50
Intramembrane proteolytic systems in cellular signaling, homeostasis and quality control, K. Stříšovský
09:50 – 10:40
Small molecules as tools for dissectingh signalling pathways, P. Bartůněk
11:00 – 11:50
Membrane heterogenity: Dynamic nanodomains, lipid shels a realistic model?, V. Hořejší
MODULE:

Development

Monday 11. 11. 2019
09:00 – 09:50
Drosophila as a model system to study developmental processes, P. Tomančák
09:50 – 10:40
The maternal nucleolus and embryonic ribosome biogenesis, H. Fulková
11:00 – 11:50
Evolution of genes and gene expression programs – Stories of emerging functions, P. Svoboda
13:00 – 13:50
Analysis of complex plant genomes, J. Doležel
MODULE:

Genomics

Tuesday 12. 11. 2019
09:00 – 09:50
Retroviruses Advances in Molecular Genetics, J. Hejnar
09:50 – 10:40
CRISPR-based mutation screen, G. Michlits
11:00 – 11:50
Genetics of autism and intellectual disability, Z. Sedláček
13:00 – 13:50
Rare genetic variants in Mendelian and complex diseases, S. Kmoch
14:10 – 15:00
From hybrid sterility to PRDM9 histone methyltransferase and back, J. Forejt
MODULE:

Biomedicine

Wednesday 13. 11. 2019
09:00 – 09:50
Leukemogenesis: genetics vs. epigenetics, T. Stopka
09:50 – 10:40
Tumor immunology and cancer immunotherapy, R. Špíšek
11:00 – 11:50
T-cell Total Recall: Reals and Fakes of the T-cell memory, O. Štěpánek
13:00 – 13:50
DNA damage response and cell cycle checkpoints, L. Macůrek
14:10 – 15:00
Molecular tricks of host-pathogen interactions, P. Šebo
MODULE:

Career Day

Thursday 14. 11. 2019
09:00 – 10:40
Introduction into English in Academic Writing, K. Bohuslavová
11:00 – 11:50
(Research) Ethics, P. Svoboda
13:00 – 13:50
Career in Life-Sciences, D. Staněk
14:10 – 15:40
Career paths in science, Invited speakers
Research and alternatives – J. Moos (i&i Prague)
There is life after academia – M. Dienstbier (Diana Biotech)
16:00 – 17:00
Postdoc interviews, P. Svoboda
MODULE:

PhD Talks

Friday 15. 11. 2019
09:30 – 10:00
Coreceptor-bound Lck: 30-year-old mystery coming to its end, V. Horková
10:00 – 10:30
WASH complex and the retromer: the story of two endosomal complexes, V. Dostál
10:50 – 11:20
SART3 and spliceosomal assembly, K. Klimešová
11:20 – 11:50
Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments, V. Henrichs