MODULE:
DNA/nucleus
Monday 30. 10. 2023
J. Jonák/P. Svoboda
08:40 – 09:00
opening remarks & organizational items
opening remarks & organizational items, J. Jonák/P. Svoboda
P. Hozák
09:00 – 09:50
The cell nucleus: relationship between microstructure and function
The cell nucleus: relationship between microstructure and function, P. Hozák
J. Pačes
09:50 – 10:40
Human genome structure and evolution
Human genome structure and evolution, J. Pačes
P. Svoboda
11:00 – 11:50
Evolution of genes and gene expression programs
Evolution of genes and gene expression programs, P. Svoboda
J. Doležel
13:00 – 13:50
Organization and function of the 3D genome
Organization and function of the 3D genome, J. Doležel
J. Fajkus
14:10 – 15:00
Telomeres and telomerases: structure, functions and evolution
Telomeres and telomerases: structure, functions and evolution, J. Fajkus
MODULE:
RNA Biology
Tuesday 31. 10. 2023
D. Staněk
09:00 – 09:50
Alternative splicing
Alternative splicing, D. Staněk
D. Blažek
09:50 – 10:40
Cyclin-dependent kinases in transcription and splicing
Cyclin-dependent kinases in transcription and splicing, D. Blažek
Z. Paris
11:00 – 11:50
tRNA metabolism
tRNA metabolism, Z. Paris
M. O’Connell
13:00 – 13:50
dsRNA response in innate immunity/ADARs
dsRNA response in innate immunity/ADARs, M. O’Connell
P. Svoboda
14:10 – 15:00
Genome defense by small RNAs in mammals
Genome defense by small RNAs in mammals, P. Svoboda
MODULE:
Proteins
Wednesday 1. 11. 2023
L. Valášek
09:00 – 09:50
Eukaryotic protein synthesis
Eukaryotic protein synthesis, L. Valášek
J. Petrák
09:50 – 10:40
Proteomics – expectation, promises and reality
Proteomics – expectation, promises and reality, J. Petrák
P. Řezáčová
11:00 – 11:50
Protein structure determination by X-ray crystallography
Protein structure determination by X-ray crystallography, P. Řezáčová
L. Čermák
13:00 – 13:50
Protein turnover in cancer and development: insights into cellular dynamics
Protein turnover in cancer and development: insights into cellular dynamics, L. Čermák
J. Vondrášek
14:10 – 15:00
Protein structure predictions
Protein structure predictions, J. Vondrášek
MODULE:
Cell Biology, Cytoskeleton & Co.
Thursday 2. 11. 2023
Z. Lánský
09:00 – 09:50
Ensemble dynamics of cytoskeletal proteins
Ensemble dynamics of cytoskeletal proteins, Z. Lánský
Pa. Dráber
09:50 – 10:40
Microtubules and signal transduction
Microtubules and signal transduction, Pa. Dráber
V. Varga
11:00 – 11:50
Biology of eukaryotic flagella and cilia
Biology of eukaryotic flagella and cilia, V. Varga
M Gregor
13:00 – 13:50
Cytoskeletal organization in cell and tissue mechanics
Cytoskeletal organization in cell and tissue mechanics, M Gregor
S. Osmanagic-Myers
14:10 – 15:00
Nuclear mechanobiology and aging
Nuclear mechanobiology and aging, S. Osmanagic-Myers
MODULE:
Cell Biology
Friday 3. 11. 2023
J. Pláteník
09:00 – 09:50
Cellular iron as a source of oxidative stress, DNA damage and ferroptosis
Cellular iron as a source of oxidative stress, DNA damage and ferroptosis, J. Pláteník
V. Hampl
09:50 – 10:40
Mitochondria
Mitochondria, V. Hampl
A. Nadler
11:00 – 11:50
Cell biology of lipids – current challenges & approaches
Cell biology of lipids – current challenges & approaches, A. Nadler
MODULE:
Development
Monday 6. 11. 2023
H. Fulková
09:00 – 09:50
Oocyte-to-embryo transition
Oocyte-to-embryo transition, H. Fulková
L. Láníková
09:50 – 10:40
Therapeutic models in regenerative medicine and oncology
Therapeutic models in regenerative medicine and oncology, L. Láníková
P. Fabian
11:00 – 11:50
Zebrafish as a model system in developmental biology
Zebrafish as a model system in developmental biology, P. Fabian
A. Hejnol
13:00 – 13:50
Comparative developmental biology
Comparative developmental biology, A. Hejnol
O. Svoboda
14:10 – 15:00
Hematopoiesis
Hematopoiesis, O. Svoboda
MODULE:
Biomedicine, Genetics & Genomics
Tuesday 7. 11. 2023
R. Spíšek
09:00 – 09:50
Tumor immunology and cancer immunotherapy
Tumor immunology and cancer immunotherapy, R. Spíšek
M. Kolář
09:50 – 10:40
Reading biological information
Reading biological information, M. Kolář
J. Procházka
11:00 – 11:50
Epigenetic disorders: from understanding to potential therapy
Epigenetic disorders: from understanding to potential therapy, J. Procházka
R. Sedláček
13:00 – 13:50
Guided nucleases – an introduction
Guided nucleases – an introduction, R. Sedláček
R.O. Bak
14:10 – 15:00
CRISPR/Cas in biomedicine
CRISPR/Cas in biomedicine, R.O. Bak
MODULE:
Biomedicine, Cancer
Wednesday 8. 11. 2023
Z. Storchová
09:00 – 09:50
Chromosomal aberrations in cancer cells – the penalties and the rewards
Chromosomal aberrations in cancer cells – the penalties and the rewards, Z. Storchová
H. Hanzlíková
09:50 – 10:40
ADP-ribose metabolism, DNA strand breaks and human disease
ADP-ribose metabolism, DNA strand breaks and human disease, H. Hanzlíková
H. Polášek-Sedláčková
11:00 – 11:50
Regulation of DNA replication in healthy and cancer cells
Regulation of DNA replication in healthy and cancer cells, H. Polášek-Sedláčková
K. Rohlenová
13:00 – 13:50
Metabolic communication in tumors: focus on nucleotide metabolism
Metabolic communication in tumors: focus on nucleotide metabolism, K. Rohlenová
L. Macůrek
14:10 – 15:00
DNA damage response and cellular checkpoints in cancer
DNA damage response and cellular checkpoints in cancer, L. Macůrek
MODULE:
Biomedicine, Immuno
Thursday 9. 11. 2023
T. Stopka
09:00 – 09:50
Epigenetic regulation in leukemia predisposition and myelodysplastic syndromes
Epigenetic regulation in leukemia predisposition and myelodysplastic syndromes, T. Stopka
J. Starková
09:50 – 10:40
Metabolic vulnerabilities in leukemia
Metabolic vulnerabilities in leukemia, J. Starková
K. Škvárová
11:00 – 11:50
Gene editing strategies for correcting inherited bone marrow failure syndromes
Gene editing strategies for correcting inherited bone marrow failure syndromes, K. Škvárová
Pe. Dráber jun.
13:00 – 13:50
Targeting proinflammatory cytokines in autoimmune diseases
Targeting proinflammatory cytokines in autoimmune diseases, Pe. Dráber jun.
S. Kmoch
14:10 – 15:00
Rare genetic variants in Mendelian complex diseases
Rare genetic variants in Mendelian complex diseases, S. Kmoch
MODULE:
Career Development, Discussion Panel
Thursday 9. 11. 2023
D. Staněk
15:20 – 16:30
Career paths – research and alternatives
Career paths – research and alternatives, D. Staněk
16:30 – 18:00
Career reflections and decisions: open discussion with people with different career paths
Career reflections and decisions: open discussion with people with different career paths
18:00 – 22:00
dinner & socializing
dinner & socializing
MODULE:
Career Development
Friday 10. 11. 2023
P. Svoboda
09:00 – 10:10
Decision points: postdoc selection and postdoc interview
Decision points: postdoc selection and postdoc interview, P. Svoboda
P. Svoboda
10:40 – 12:00
Scientific misconduct
Scientific misconduct, P. Svoboda
12:00
Credits
Credits