Programme / Lectures – 2025

MODULE:

DNA/nucleus

Monday 3. 11. 2025
J. Jonák/P. Svoboda
08:40 – 09:00
opening remarks & organizational items
opening remarks & organizational items, J. Jonák/P. Svoboda
J. Hejnar
09:00 – 09:50
CRISPR/Cas9-based antiviral strategies
CRISPR/Cas9-based antiviral strategies, J. Hejnar
P. Hozák
09:50 – 10:40
Compartmentalization of the cell nucleus and phase separation
Compartmentalization of the cell nucleus and phase separation, P. Hozák
R. Foisner
11:00 – 11:50
Nuclear lamins and associated proteins: from structure to function in health and disease (virtual)
Nuclear lamins and associated proteins: from structure to function in health and disease (virtual), R. Foisner
J. Pačes
13:00 – 13:50
Oganization of human genome
Oganization of human genome, J. Pačes
A. Pombo
14:10 – 15:00
Spatio-temporal organization of the cell nucleus (virtual)
Spatio-temporal organization of the cell nucleus (virtual), A. Pombo
MODULE:

RNA Biology

Tuesday 4. 11. 2025
L. Krásný
09:00 – 09:50
RNA polymerase and bacterial transcription
RNA polymerase and bacterial transcription, L. Krásný
J. Hnilicová
09:50 – 10:40
Non-coding RNAs
Non-coding RNAs, J. Hnilicová
S. Vaňáčová
11:00 – 11:50
RNA modifications
RNA modifications, S. Vaňáčová
M. O’Conell
13:00 – 13:50
RNA and innate immunity
RNA and innate immunity, M. O’Conell
D. Staněk
14:10 – 15:00
Alternative splicing regulation
Alternative splicing regulation, D. Staněk
MODULE:

Proteins

Wednesday 5. 11. 2025
L. Valášek
09:00 – 09:50
Eukaryotic protein synthesis
Eukaryotic protein synthesis, L. Valášek
J. Petrák
09:50 – 10:40
Unveiling the proteomes: capabilities and challenges of current proteomics
Unveiling the proteomes: capabilities and challenges of current proteomics, J. Petrák
Pavlína Maloy Řezáčová
11:00 – 11:50
Structural biology tools
Structural biology tools, Pavlína Maloy Řezáčová
K. Holada
13:00 – 13:50
Prions, prion strains and expanding universe of prion diseases
Prions, prion strains and expanding universe of prion diseases, K. Holada
K. Hlouchová
14:10 – 15:00
Insight into Synthetic biology
Insight into Synthetic biology, K. Hlouchová
MODULE:

Cell Biology, Cytoskeleton & Co.

Thursday 6. 11. 2025
T. Middelkoop
09:00 – 09:50
Actomyosin-driven early embryo morphogenesis
Actomyosin-driven early embryo morphogenesis, T. Middelkoop
A. Mitra
09:50 – 10:40
Biophyscis of ciliary transport
Biophyscis of ciliary transport, A. Mitra
M. Gregor
11:00 – 11:50
Integrative biology
Integrative biology, M. Gregor
G. Forte
13:00 – 13:50
Interaction between tissue-specific cells and the extracellular matrix
Interaction between tissue-specific cells and the extracellular matrix, G. Forte
Pa. Dráber
14:10 – 15:00
Microtubules and signal transduction
Microtubules and signal transduction, Pa. Dráber
MODULE:

Cell Biology

Friday 7. 11. 2025
D. Rozbeský
09:00 – 09:50
Molecular mechanisms of axon guidance
Molecular mechanisms of axon guidance, D. Rozbeský
M. Huranová
09:50 – 10:40
Cilia in health and disease
Cilia in health and disease, M. Huranová
V. Hampl
11:00 – 11:50
Diversity of mitochondria
Diversity of mitochondria, V. Hampl
MODULE:

Development

Monday 10. 11. 2025
I. Kozmiková
09:00 – 09:50
Evo-Devo
Evo-Devo, I. Kozmiková
A. W. Bruce
09:50 – 10:40
Early mouse development
Early mouse development, A. W. Bruce
P. Fabian
11:00 – 11:50
Zebrafish as a model system in developmental biology
Zebrafish as a model system in developmental biology, P. Fabian
J. Harnoš
13:00 – 13:50
Xenopus as a model system in developmental biology
Xenopus as a model system in developmental biology, J. Harnoš
J. Glaser
14:10 – 15:00
Transposable elements in mammalian development
Transposable elements in mammalian development, J. Glaser
MODULE:

Biomedicine, Genetics & Genomics

Tuesday 11. 11. 2025
S. Kmoch
09:00 – 09:50
Rare genetic variants in Mendelian and complex diseases
Rare genetic variants in Mendelian and complex diseases, S. Kmoch
M. Kolář
09:50 – 10:40
Reading biological information
Reading biological information, M. Kolář
P. Cígler
11:00 – 11:50
RNA delivery particles
RNA delivery particles, P. Cígler
J. Prochazka
13:00 – 13:50
Epigenetic disorders: from understanding to potential therapy
Epigenetic disorders: from understanding to potential therapy, J. Prochazka
D. Lainscek
14:10 – 15:00
Genome editing using CRISPR/Cas system (virtual)
Genome editing using CRISPR/Cas system (virtual), D. Lainscek
MODULE:

Biomedicine, Cancer

Wednesday 12. 11. 2025
J. Neužil
09:00 – 09:50
Horizontal mitochondrial transfer as a new hallmark of cancer
Horizontal mitochondrial transfer as a new hallmark of cancer, J. Neužil
L. Macůrek
09:50 – 10:40
Canonical and novel functions of the tumor suppressor p53
Canonical and novel functions of the tumor suppressor p53, L. Macůrek
K. Rohlenová
11:00 – 11:50
Metabolic communication in tumor environment
Metabolic communication in tumor environment, K. Rohlenová
L. Krejčí
13:00 – 13:50
DNA repair and its relevance to human pathologies
DNA repair and its relevance to human pathologies, L. Krejčí
Z. Štorchová
14:10 – 15:00
Chromosomal aberrations in cancer cells – the penalties and the rewards
Chromosomal aberrations in cancer cells – the penalties and the rewards, Z. Štorchová
MODULE:

Biomedicine, Immuno

Thursday 13. 11. 2025
M. Šimíček
09:00 – 09:50
CAR-T: from biology to clinics
CAR-T: from biology to clinics, M. Šimíček
J. Starková
09:50 – 10:40
Metabolic rewiring in leukemia therapy resistance and advanced treatment strategies
Metabolic rewiring in leukemia therapy resistance and advanced treatment strategies, J. Starková
R. Špíšek
11:00 – 11:50
Tumor immunology and cancer immunotherapy
Tumor immunology and cancer immunotherapy, R. Špíšek
L. Láníková
13:00 – 13:50
Oxygen transport at the molecular level: from gene regulation to human performance
Oxygen transport at the molecular level: from gene regulation to human performance, L. Láníková
M. Mráz
14:10 – 15:00
Non-coding RNAs in the biology of mature B cell leukemias and lymphomas
Non-coding RNAs in the biology of mature B cell leukemias and lymphomas, M. Mráz
MODULE:

Career Development, Discussion Panel

Thursday 13. 11. 2025
P. Svoboda
15:20 – 16:30
Academic Ecosystem
Academic Ecosystem, P. Svoboda
16:30 – 18:00
Career reflections and decisions: open discussion with people with different career paths
Career reflections and decisions: open discussion with people with different career paths
18:00 – 22:00
dinner & socializing
dinner & socializing
MODULE:

Career Development

Friday 14. 11. 2025
P. Svoboda
09:00 – 10:10
Scientific misconduct
Scientific misconduct, P. Svoboda
P. Svoboda
10:40 – 12:00
Conflict management
Conflict management, P. Svoboda
12:00
Credits
Credits

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