Programme / Lectures – 2021

MODULE:

DNA/nucleus

Monday 1. 11. 2021
08:30 – 09:30
registration, refreshment
registration, refreshment
J. Jonák/P. Svoboda
09:30 – 09:50
opening remarks
opening remarks, J. Jonák/P. Svoboda
P. Hozák
09:50 – 10:40
The cell nucleus: relationship between microstructure and function
The cell nucleus: relationship between microstructure and function, P. Hozák
J. Fajkus
11:00 – 11:50
Plant telomeres
Plant telomeres, J. Fajkus
J. Hejnar
13:00 – 13:50
Retroviruses. Arm Race between Virus and Cell
Retroviruses. Arm Race between Virus and Cell, J. Hejnar
D. Odom
14:10 – 15:00
Lesion segregation as a novel mechanism shaping cancer genome evolution
Lesion segregation as a novel mechanism shaping cancer genome evolution, D. Odom
MODULE:

RNA Biology

Tuesday 2. 11. 2021
M. Frey
09:00 – 09:50
RNA 5‐methylcytosine drives metabolic reprogramming required for metastasis
RNA 5‐methylcytosine drives metabolic reprogramming required for metastasis, M. Frey
D. Staněk
09:50 – 10:40
Alternative splicing regulation
Alternative splicing regulation, D. Staněk
L. Krásný
11:00 – 11:50
The RNAP Vehicle: Starting and Stopping
The RNAP Vehicle: Starting and Stopping, L. Krásný
P. Svoboda
13:00 – 13:50
Small RNAs in mammalian germ cells
Small RNAs in mammalian germ cells, P. Svoboda
Š. Vanáčová
14:10 – 15:00
Do I talk to Me?
Do I talk to Me?, Š. Vanáčová
MODULE:

Proteins

Wednesday 3. 11. 2021
J. Petrák
09:00 – 09:50
Proteomics – expectations and the reality
Proteomics – expectations and the reality, J. Petrák
P. Řezáčová
09:50 – 10:40
Protein structure determination by X‐ray crystallography
Protein structure determination by X‐ray crystallography, P. Řezáčová
K. Kubíček
11:00 – 11:50
Cryo EM: From organelles to atomic-resolution structures of molecules inside the cell
Cryo EM: From organelles to atomic-resolution structures of molecules inside the cell, K. Kubíček
L. Čermák
13:00 – 13:50
Protein‐degradation ‐ ubiquitin ligases
Protein‐degradation ‐ ubiquitin ligases, L. Čermák
J. Vondrášek
14:10 – 15:00
Protein structure predictions
Protein structure predictions, J. Vondrášek
MODULE:

Cell Biology

Thursday 4. 11. 2021
L. Valášek
09:00 – 09:50
Eukaryotic protein synthesis
Eukaryotic protein synthesis, L. Valášek
V. Varga
09:50 – 10:40
Biology of eukaryotic flagella and cilia
Biology of eukaryotic flagella and cilia, V. Varga
Pa. Dráber
11:00 – 11:50
Microtubules and signal transduction
Microtubules and signal transduction, Pa. Dráber
A. Sumová
13:00 – 13:50
Biological clock
Biological clock, A. Sumová
J. Pláteník
14:10 – 15:00
Cellular iron as a source of oxygen radicals and DNA damage
Cellular iron as a source of oxygen radicals and DNA damage, J. Pláteník
MODULE:

Signaling

Friday 5. 11. 2021
H. Hanzlíková
09:00 – 09:50
Sensing and repairing DNA strand breaks
Sensing and repairing DNA strand breaks, H. Hanzlíková
V. Bryja
09:50 – 10:40
Wnt signaling
Wnt signaling, V. Bryja
V. Hořejsí
11:00 – 11:50
Membrane microdomains and their biological roles ‐ facts and artifacts
Membrane microdomains and their biological roles ‐ facts and artifacts, V. Hořejsí
MODULE:

Development

Monday 8. 11. 2021
P. Hájková
09:00 – 09:50
germline reprogramming
germline reprogramming, P. Hájková
H. Fulková
09:50 – 10:40
oocyte‐to‐embryo transition
oocyte‐to‐embryo transition, H. Fulková
P. Bartůněk
11:00 – 11:50
hematopoiesis
hematopoiesis, P. Bartůněk
M. Jindra
13:00 – 13:50
Insect development
Insect development, M. Jindra
J. Mašek
14:10 – 15:00
Notch signaling in development
Notch signaling in development, J. Mašek
MODULE:

Genetics & Genomics

Tuesday 9. 11. 2021
J. Pačes
09:00 – 09:50
Strucutre and evolution of the SARS‐CoV‐2 genome
Strucutre and evolution of the SARS‐CoV‐2 genome, J. Pačes
S. Kmoch
09:50 – 10:40
Rare genetic variants in Mendelian complex diseases
Rare genetic variants in Mendelian complex diseases, S. Kmoch
Z. Sedláček
11:00 – 11:50
Genetics of intellectual disability and autism
Genetics of intellectual disability and autism, Z. Sedláček
R. Sedláček
13:00 – 13:50
CRISPR
CRISPR, R. Sedláček
J. Doležel
14:10 – 15:00
Organization and function of the 3D genome
Organization and function of the 3D genome, J. Doležel
MODULE:

Biomedicine (pathogens)

Wednesday 10. 11. 2021
O. Štěpánek
09:00 – 09:50
Adaptive immunity
Adaptive immunity, O. Štěpánek
K. Holada
09:50 – 10:40
Prions
Prions, K. Holada
P. Šebo
11:00 – 11:50
Molecular and genetic bases of bacterial virulence
Molecular and genetic bases of bacterial virulence, P. Šebo
L. Macůrek
13:00 – 13:50
DNA damage response and cellular checkpoints in cancer
DNA damage response and cellular checkpoints in cancer, L. Macůrek
R. Spíšek
14:10 – 15:00
Tumor immunology and cancer immunotherapy
Tumor immunology and cancer immunotherapy, R. Spíšek
MODULE:

Career Development

Thursday 11. 11. 2021
P. Svoboda
09:00 – 09:50
Scientific misconduct
Scientific misconduct, P. Svoboda
K. Bohuslavová
10:00 – 11:50
Introduction into English in Academic Writing
Introduction into English in Academic Writing, K. Bohuslavová
D. Staněk, P. Svoboda
13:00 – 14:30
Career paths & interviews
Career paths & interviews, D. Staněk, P. Svoboda
MODULE:

PhD/postdoc discussion panel

Thursday 11. 11. 2021
14:45 – 15:45
Movie – Naturally Obsessed – The Making of a Scientist (document)
Movie – Naturally Obsessed – The Making of a Scientist (document)
discussion panel
16:00 – 17:30
Career in science
Career in science, discussion panel
17:30 – 21:00
Social event
Social event
MODULE:

PhD Talks

Friday 12. 11. 2021
L. Knoblochová
09:30 – 10:00
Chk1 kinase is essential for DNA integrity protection during early embryonic development in mice
Chk1 kinase is essential for DNA integrity protection during early embryonic development in mice, L. Knoblochová
Z. Loubalová
10:00 – 10:30
piRNA pathway in Golden hamsters
piRNA pathway in Golden hamsters, Z. Loubalová
O. Tsyklauri
10:50 – 11:20
Tregs in autoimmunity and cancer
Tregs in autoimmunity and cancer, O. Tsyklauri
S. Grusanovic
11:20 – 11:50
Chronic inflammation instructs hematopoietic stem cells to lose their fitness
Chronic inflammation instructs hematopoietic stem cells to lose their fitness, S. Grusanovic